2022年

66. Long-Fei Nan, Xiu-Shuai Chen, Hao Chen, Xin-Hu Hu, Xin-Hong Wang* and Xiang-Ping Hu* Development of spirocyclic phosphoramidite-based hybrid diphosphorus ligands for enantioselective iridium-catalyzed hydrogenation of imines. Org. Biomol. Chem. 2022, 20, 8420-8424. Full Text PDF

65. Jing-Bo Ma, Xin-Hong Wang,* Zhen-Ting Liu* and Xiang-Ping Hu Highly diastereo- and enantioselective copper-catalyzed dipropargylic amination to access bispropargylic diamines. Asian J. Org. Chem. 2022, 11, e202200385. Full Text PDF

64. Hong-Quan Du* Rh-catalyzed asymmetric hydrogenation of α- and β-enamido phosphonates: highly enantioselective access to amino phosphonic acids. Org. Biomol. Chem. 2022, 20, 8843-8848. Full Text PDF

63. Yin-Bo Wan, Xiang-Ping Hu* Highly Enantioselective Iridium-Catalyzed Hydrogenation of o‑Amidophenyl Ketones Enabled by 1,2-DiphenylethylenediamineDerived P,N,N-Ligands with Tertiary Amine Terminus. Org. Lett. 2022, 24, 5797-5801. Full Text PDF

62. Ling Li, Xiu-Shuai Chen, Xiang-Ping Hu* Intramolecular Copper-Catalyzed Asymmetric Propargylic [4+2]-Cycloaddition toward Optically Active Tetrahydroisoindolo[2,1-a]quinoxalines. Org. Lett. 2022, 24, 5433-5438.Full Text PDF

2021年

61. Hong-Quan Du, Xiang-Ping Hu* Bicyclic Bridgehead Phosphoramidite-Based Hybrid Diphosphorus Ligands: Design, Synthesis, and Application in Catalytic Asymmetric Hydrogenation. Org. Lett. 2021, 23, 7678-7682. Full Text PDF

60. Jin-Tao Xia, Ling Li, Xiang-Ping Hu* Copper-Catalyzed Decarboxylative Propargylic Alkylation of Enol Carbonates: Stereoselective Synthesis of Quaternary α-Amino Acids. ACS Catal. 2021, 11, 11843–11848.Full Text PDF

59. Ling Li, Zhen-Ting Liu*, Xiang-Ping Hu* Copper-catalyzed one-pot cascade cyclization for the synthesis of isoindolo[2,1-a]quinoxalines. Adv. Synth. Catal. 2021, 363, 4272-4276.  Full Text PDF

58. Chao Dong, Dao-Sheng Liu, Lei Zhang*, Xiang-Ping Hu* Rh-catalyzed asymmetric hydrogenation of α-aryl-β-alkylvinyl esters with chiral ferrocenylphosphine-phosphoramidite ligand. Tetrahedron Lett. 2021, 65, 152763. Full Text PDF

2020年

57. You-Wei Xu, Ling Li, Xiang-Ping Hu* Enantioselective copper-catalyzed [3+3] cycloaddition of tertiary propargylic esters with 1H‑Pyrazol-5(4H)‑ones toward optically active spirooxindoles. Org. Lett. 2020, 22, 9534–9538. Full Text PDF

56. Jin-Tao Xia, Xiang-Ping Hu* Copper-catalyzed asymmetric propargylic alkylation with oxindoles: Diastereo- and enantioselective construction of vicinal tertiary and all-carbon quaternary stereocenters. Org. Lett. 2020, 22, 1102–1107.Full Text PDF

55. Zaheer Abbas, Xin-Hu Hu, Aijaz Ali, You-Wei Xu, Xiang-Ping Hu* New chiral ferrocene/indole-based diphosphine ligands for Rh-catalyzed asymmetric hydrogenation of functionalized olefins. Tetrahedron Lett. 2020, 61, 151860.Full Text PDF

54. Jiao Han, You-Wei Xu, Xue-Ming Wang, Lei Zhang, Xiang-Ping Hu* Copper-catalyzed formal propargylic [3+2] cycloaddition for stereoselective construction of (E)-β-pyrazolylacrylates. Tetrahedron Lett. 2020, 61, 151409.Full Text PDF

 

2019年

53. Xin-Hu Hu, Xiang-Ping Hu*. Highly diastereo- and enantioselective Ir-catalyzed hydrogenation of 2,3-disubstituted quinolines with structurally fine-tuned phosphine-phosphoramidite ligands. Org. Lett. 2019, 21, 10003-10006. Full Text PDF

52. De-Quan Wei, Zhen-Ting Liu, Xue-Ming Wang, Chuan-Jin Hou, Xiang-Ping Hu* Copper-catalyzed asymmetric propargylic etherification of oximes promoted by chiral tridentate P,N,N-ligand. Tetrahedron Lett. 2019, 60, 151305.Full Text PDF

51. Hong-Quan Du, Xiang-Ping Hu* Rh-catalyzed asymmetric hydrogenation of (Z)‑β-phosphorylated
enamides: Highly enantioselective access to β‑aminophosphines. Org. Lett. 2019, 21, 8921-8924. Full Text PDF

50. Xin-Hu Hu, Xiang-Ping Hu*. Ir-Catalyzed asymmetric hydrogenation of α-imino esters with chiral ferrocenylphosphine-phosphoramidite ligands. Adv. Synth. Catal. 2019, 361, 5063–5068. Full Text PDF

49. You-Wei Xu, Xiang-Ping Hu*. Diastereo- and enantioselective copper-catalyzed decarboxylative ring-opening [3+2] annulation of tertiary propargylic carbamates through regioselective α-attack of γ-butenolides. Org. Lett. 2019, 21, 8091−8096. Full Text PDF

48. Zhen-Ting Liu, Xiang-Ping Hu*. Palladium-catalyzed propargylic [n+2] cycloaddition: An efficient strategy for construction of benzo-fused medium-sized heterocycles. Adv. Synth. Catal. 2019, 361, 836-841.Full Text PDF

2018年

47. Zhen-Ting Liu, Xiang-Ping Hu*. Copper-catalyzed, silver-mediated formal [3+2] cycloaddition of simple alkynes with β-ketoesters through propargylic C(sp3)-H functionalization. Chem. Commun. 2018, 54, 14100-14103 .Full Text PDF

46. Kun Li, Fu-Lin Zhu, Zhen-Ting Liu, Jing Tong*, Xiang-Ping Hu*. Decarboxylation-promoted Pd-catalyzed asymmetric propargylic [3+2] annulation for the enantioselective construction of a quaternary stereocenter in 2,3-dihydrofurans. Org. Biomol. Chem. 2018, 16, 742-749.Full Text PDF

45. Ling Li, Zhen-Ting Liu, Xiang-Ping Hu*. Copper-catalyzed propargylic [3+3] cycloaddition with 1H-pyrazol-5(4H)-ones: enantioselective access to optically active dihydropyrano[2,3-c]-pyrazoles. Chem. Commun. 2018, 54, 12033-12036.Full Text PDF

2017年

44. Long Shao, Xiang-Ping Hu*. Copper-catalyzed intermolecular asymmetric propargylic dearomatization of phenol derivatives. Chem. Commun. 2017, 53, 8192-8195.Full Text PDF

43. Long Shao, Xiang-Ping Hu*. Cu-Catalyzed asymmetric Friedel-Crafts propargylic alkylation of phenol derivatives. Org. Biomol. Chem. 2017, 15, 9837-9844.Full Text PDF

42. Fu-Zhong Han*, Bo-Bo Su, Li-Na Jia, Peng-Wei Wang, Xiang-Ping Hu*.Quaternary ammouium salt-promotesd multi-component reaction in water: access to 3-alkyl-2,3-dihydro-1H-isoindolin-1-one derivatives. Adv. Synth. Catal. 2017, 359, 146-152.Full Text PDF

41. Xiu-Shuai Chen, Chuan-Jin Hou*,Chao Qin, Hong-Zhu Liu, Yan-Jun Liu, De-Zhi Huang, Xiang-Ping Hu*. Ir-catalyzed asymmetric hydrogenation of b-keto esters with chiral ferrocenyl P,N,N-ligands. RSC Adv. 2017, 7, 12871-12875.Full Text PDF

2016年

40. Chuan-Jin Hou, Xiang-Ping Hu*. Sterically hindered chiral ferrocenyl P,N,N-ligands for highly diastereo-/enantioselective Ir-catalyzed hydrogenation of α-alkyl-β-ketoesters via dynamic kinetic resolution.Org. Lett. 2016, 18, 5592-5595.Full Text PDF

39. Long Shao, De-Yang Zhang, Ya-Hui Wang, Xiang-Ping Hu*. Enantioselective copper-catalyzed propargylic etherification of propargylic esters with phenols promoted by inorganic base additives. Adv. Synth. Catal. 2016, 358, 2558-2563.Full Text PDF

38. Xiu-Shuai Chen, Chuan-Jin Hou*,Qing Li, Yan-Jun Liu*, Rui-Feng Yang, Xiang-Ping Hu*. Enantioselective synthesis of chiral phosphonylated 2,3-dihydrofurans by copper catalyzed asymmetric formal [3+2] cycloaddition of propargylic esters with b-keto phosphonates. Chin. J. Catal. 2016, 37, 1389-1395.Full Text PDF

37. Xiu-Shuai Chen, Chuan-Jin Hou*, Xiang-Ping Hu*. Chiral phosphine-phosphoramidite ligands in asymmetric catalysis. Synth. Commun. 2016, 46, 917-941.Full Text PDF

36.  Yong Zhou, Fu-Lin Zhu, Zhen-Ting Liu, Xiao-Mao Zhou*, Xiang-Ping Hu*. Chiral Ferrocenyl P,N-Ligands for Palladium-Catalyzed Asymmetric Formal [3 + 2] Cycloaddition of Propargylic Esters with β-Ketoesters: Access to Functionalized Chiral 2,3-Dihydrofurans. Org. Lett. 2016, 18,234-2737.Full Text PDF

35. Long Shao, Ya-Hui Wang, De-Yang Zhang, Jie Xu, Xiang-Ping Hu*. Desilylation-Activated Propargylic Transformation: Enantioselective Cu-Catalyzed [3+2] Cycloaddition of Propargylic Esters with β-Naphthol or Phenol Derivatives. Angew. Chem. Int. Ed. 2016, 55, 5014-5018.Full Text PDF

34. Zhen-Ting Liu, Ya-Hui Wang, Fu-Lin Zhu, Xiang-Ping Hu*. Enantioselective Copper-Catalyzed Formal [4 + 2] Cycloaddition of o-Aminophenol Derivatives with Propargylic Esters for Synthesis of Optically Active 3,4-Dihydro-2H-1,4-benzoxazines. Org. Lett. 2016, 18, 1190-1194.Full Text PDF

33. Fu-Zhong Han, Sai-Bo Yu, Cheng Zhang, Xiang-Ping Hu*. Chiral ferrocenyl P,S-ligands for highly efficient copper-catalyzed asymmetric [3+2] cycloaddition of azomethine ylides. Tetrahedron. 2016, 72, 2616-2622.Full Text PDF

32. Cheng Zhang, Yun-Ze Hui, De-Yang Zhang, Xiang-Ping Hu*. Highly diastereo-/enantioselective Cu-catalyzed propargylic alkylations of propargyl acetates with cyclic enamines. RSC Adv. 2016, 6, 14763-14767.Full Text PDF

2015年

31. De-Yang Zhang , Long Shao, Jie Xu, Xiang-Ping Hu*.Copper-Catalyzed Asymmetric Formal [3 + 2] Cycloaddition of Propargylic Acetates with Hydrazines: Enantioselective Synthesis of Optically Active 2‑Pyrazolines. ACS Catal. 2015, 5, 5026-5030.Full Text PDF(Cover Paper)

30. Qing-Li, Yun-Ze Hui, Chuan-Jin Hou*, Yan-Jun Liu, Rui-Feng Yang, Xiang-Ping Hu*. Tridentate P,N,N-ligand promoted copper-catalyzed [3+2] cycloaddition of propargylic esters with β-enamino esters: synthesis of highly functionalized pyrroles. RSC Adv. 2015, 5, 85879-85883.Full Text PDF

29. Xin-Hu Hu, Zhen-Ting Liu, Long Shao, Xiang-Ping Hu*. Recent advances in catalytic stereo-controlled cycloaddition with terminal propargylic compounds. Synthesis 2015, 47, 913-923. (Invited Review)Full Text PDF

28. Qing-Li, Chuan-Jin Hou*, Yan-Jun Liu, Rui-Feng Yang, Xiang-Ping Hu*. Asymmetric hydrogenation of α-keto phosphonates with chiral phosphine-phosphoramidite ligands. Tetrahedron: Asymmetry. 2015, 26, 617-622.Full Text PDF

27. Qing-Li, Chuan-Jin Hou*, Xiao-Ning Liu, De-Zhi Huang*, Yan-Jun Liu, Rui-Feng Yang, Xiang-Ping Hu*. Chiral phosphine-phosphoramidite ligands for highly enantioselective hydrogenation of N-arylimines. RSC Adv. 2015, 5, 13702-13708.Full Text PDF

26. De-Yang Zhang, Xiang-Ping Hu*. Recent advances in copper-catalyzed propargylic substitution. Tetrahedron Lett. 2015, 56, 283-295. (Invited Review)Full Text PDF

25. Fu-Lin Zhu, Xiang-Ping Hu*. Enantioselective N‐propargylation of indoles via Cu-catalyzed propargylic alkylation/dehydrogenation of indolines. Chin. J. Catal. 2015, 35, 86-92.Full Text PDF

2014年

24. Fu-Lin Zhu, Ya-Hui Wang, De-Yang Zhang, Jie Xu, Xiang-Ping Hu*. Enantioselective Synthesis of Highly Functionalized Dihydrofurans via Copper-Catalyzed Asymmetric Formal [3+2] Cycloaddition of β-Ketoesters with Propargylic Esters withß-Keto Acids. Angew. Chem. Int. Ed. 2014, 53, 10223-10227.Full Text PDF

23. Fu-Lin Zhu, Yuan Zou, De-Yang Zhang, Ya-Hui Wang, Xin-Hu Hu, Song Chen, Jie Xu*, Xiang-Ping Hu*. Enantioselective Copper-Catalyzed Decarboxylative Propargylic Alkylation of Propargyl β-Ketoesters with a Chiral Ketimine P,N,N-Ligand. Angew. Chem. Int. Ed. 2014, 53, 1410-1414.Full Text PDF

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22. De-Yang Zhang, Fu-Lin Zhu, Ya-Hui Wang, Xin-Hu Hu, Song Chen, Chuan-Jin Hou, Xiang-Ping Hu*. Highly diastereo- and enantioselective copper-catalyzed propargylic alkylation of acyclic ketone enamines for the construction of two vicinal stereocenters. Chem. Commun. 2014, 50, 14459-14462.Full Text PDF

21. Fu-Lin Zhu, Ya-Hui Wang, De-Yang Zhang, Xin-Hu Hu, Song Chen, Chuan-Jin Hou, Jie Xu, Xiang-Ping Hu*. Enantioselective Copper-Catalyzed Decarboxylative Propargylic Alkylation of Propargylic Esters with β-Keto Acids. Adv. Synth. Catal. 2014, 356, 3231-3236.Full Text PDF

20. Yuan Zou, Fu-Lin Zhu, Zheng-Chao Duan, Ya-Hui Wang, De-Yang Zhang, Zhong Cao, Zhuo Zheng, Xiang-Ping Hu*. Enantioselective Cu-catalyzed decarboxylative propargylic amination of propargyl carbamates. Tetrahedron Lett. 2014, 55, 2033-2036.Full Text PDF

19. Fu-Zhong Han, Fu-Lin Zhu, Ya-Hui Wang, Yuan Zou, Xin-Hu Hu, Song Chen, Xiang-Ping Hu*. Highly enantioselective copper-catalyzed propargylic substitution of propargylic acetates with 1,3-diczrbonyl compounds.Org. Lett. 2014, 16, 588-591.Full Text PDF

18. Zhengchao Duan*, Lianzhi Wang, Xiaoyu Zuo, Xiangping Hu*, Zhuo Zheng. Rh-ImiFerroPhos complexes catalyzed asymmetric hydrogenation of β‐substituted α,β‐unsaturated phosphonates. Chin. J. Catal. 2014, 35, 227–231.Full Text PDF

2013年

17. Hongchao Guo*, Honglei Liu, Fu-Lin Zhu, Risong Na, Hui Jiang, Yang Wu, Lei Zhang, Zhen Li, Hao Yu, Bo Wang, Yumei Xiao, Xiang-Ping Hu*, Min Wang. Enantioselective Copper-Catalyzed [3+3] Cycloaddition of Azomethine Ylides with Azomethine Imines. Angew. Chem. Int. Ed. 2013, 52, 12641-12645.Full Text PDF

16. Dong Wang, Chuan-Jin Hou*, Li-Feng Chen, Xiao-Ning Liu, Qing-Da An*, Xiang-Ping Hu*. Progress on the Catalytic Asymmetric Hydrogenation of Imines. Chin. J. Org. Chem. 2013, 33, 1355-1368. (Review, in Chinese.Cover Paper)Full Text PDF

15. Xiao-Ning Liu, Wei-Lei Guo, Chuan-JIn Hou*, Xiang-Ping Hu*. New and Efficient Synthesis of 1,3-Dienylphosphonates by Palladium-Catalyzed Substitution of Propargylic Esters to Diethyl Phosphite. Synth. Commun. 2013, 43, 2622-2626. Full Text PDF

14. Sheng Yan, Cheng Zhang, Ya-Hui Wang, Zhong Cao*, Zhuo Zheng, Xiang-Ping Hu*. Synthesis of new chiral ferrocenyl P,N-ligands with a benzoxazole ring and their application in Ag-catalyzed asymmetric [3+2] cycloaddition. Tetrahedron Lett. 2013, 54, 3669-3672. Full Text PDF

2012年

13. Cheng Zhang, Xin-Hu Hu, Ya-Hui Wang, Zhuo Zheng, Jie Xu, Xiang-Ping Hu*. Highly Diastereo-/Enantioselective Cu-Catalyzed [3+3] Cycloaddition of Propargyl Esters with Cyclic Enamines toward Chiral Bicyclo[n.3.1] Frameworks. J. Am. Chem. Soc. 2012, 134, 9585-9588.Full Text PDF

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12. Cheng Zhang, Ya-Hui Wang, Xin-Hu Hu, Zhuo Zheng, Jie Xu, Xiang-Ping Hu*. Chiral Tridentate P,N,N Ligands for Highly Enantioselective Copper-Catalyzed Propargylic Amination with both Primary and Secondary Amines as Nucleophiles. Adv. Synth. Catal. 2012, 354, 2854-2858.Full Text PDF

11. Chuan-Jin Hou , Ya-Hui Wang, Zhuo Zheng, Jie Xu, Xiang-Ping Hu*. Chiral Phosphine-Phosphoramidite Ligands for Highly Efficient Ir-Catalyzed Asymmetric Hydrogenation of Sterically Hindered N-Arylimines. Org. Lett. 2012, 14, 3554-3557.Full Text PDF

10. Juan Hu, Dao-Yong Wang, Zhuo Zheng,Xiang-Ping Hu*. Ir-Catalyzed Enantioselective Hydrogenation of 2H-1,4-Benzoxazines with a Chiral 1,2,3,4-Tetrahydro-1-naphthylamine Derived Phosphine-aminophosphine Ligand. Chin. J. Chem. 2012, 30, 2664-2668.Full Text PDF

9. Juan Hu, Dao-Yong Wang, Zhuo Zheng, Xiang-Ping Hu*. Rh-catalyzed Asymmetric Hydrogenation of a-Enol Ester Phosphonates with 1-Phenylethylamine-Derived Phosphine-phosphoramidite Ligands. J. mol. Catal. (China) 2012, 26, 487-492. (in Chinese)Full Text PDF

8. Zheng-Chao Duan*, Lian-zhi Wang, Xiang-Ping Hu*, Zhuo Zheng. Chiral Bis(1-ferrocenylethyl) amine-derived Monophosphoramidite Ligands for Rh-catalyzed Asymmetric Hydrogenation.J. mol. Catal. (China) 2012, 26, 328-332. (in Chinese)Full Text PDF

7. Chuan-JIn Hou*, Ying Xia, Xiao-Ning Liu, Xiang-Ping Hu*. Progress on Unsymmetrical Hybrid Chiral Phosphine-phosphoramidite Ligands and Their Application in Asymmetric Catalytic Reactions. Chin. J. Org. Chem. 2012, 32, 2239-2247. (Review, in Chinese)Full Text PDF

6. Zheng-Chao Duan*, Lian-zhi Wang, Xin-jian Song,Xiang-Ping Hu*, Zhuo Zheng. Enantioselective synthesis of optically active alkylphosphonates via Rh-catalyzed asymmetric hydrogenation of β-substituted α,β-unsaturated phosphonates.Tetrahedron: Asymmetry. 2012, 23, 508-514.Full Text PDF

5. Mei-Ling Han, Dao-Yong Wang, Pei-Wei Zeng, Zhuo Zheng, Xiang-Ping Hu*. New chiral ferrocenyl P,S-ligands for highly diastereo- and enantioselective Ag(I)-catalyzed asymmetric [3+2] cycloaddition of azomethine ylides.Tetrahedron: Asymmetry. 2012, 23, 306-312.Full Text PDF

2011年

4. Wei-Lei Guo, Chuan-Jin Hou*,Zheng-Chao Duan, Xiang-Ping Hu*. An enantioselective synthesis of 3-aryl-4-phosphonobutyric acids esters via Cu-catalyzed asymmetric conjugate reduction.Tetrahedron: Asymmetry. 2011,22, 2161-2164.Full Text PDF

3. Li-Bin Luo, Dao-Yong Wang, Xiao-Mao Zhou*, Zhuo Zheng, Xiang-Ping Hu*. Asymmetric synthesis of 2-alkyl-3-phosphonopropanoic acid derivatives via Rh-catalyzed asymmetric hydrogenation. Tetrahedron: Asymmetry. 2011, 22, 2117-2123.Full Text PDF

2. Mei-Ling Han, Xiang-Ping Hu,* Jia-Di Huang, Li-Gong Chen, Zhuo Zheng*. New chiral amino alcohol ligands derived from 1-phenylethylamine for efficient Ru-catalyzed asymmetric transfer hydrogenation. Tetrahedron: Asymmetry. 2011, 22, 222-225. Full Text PDF

1. Chuan-Jin Hou, Wei-Lei Guo, Xiang-Ping Hu,*Jun Deng, Zhuo Zheng*. Chiral ferrocenyl phosphine-phosphoramidite ligands for Cu-catalyzed asymmetric conjugate reduction of α,β-unsaturated esters. Tetrahedron: Asymmetry. 2011, 22, 195-199.Full Text PDF